The wet granulation process in two separate steps is mostly recommended and suitable for conventional equipment like the High-speed Mixer & Granulator, Fluid-bed Dryer & Granulator…

This single-step granulation process provides effervescent granules directly by granulating the acid and the alkaline materials together. It is possible to use only water as the granulating liquid, thus controlling the effervescent reaction to granulate, or using a nonreactive liquid, like absolute ethanol or isopropanol, but in this case, it is necessary to use a binder to get the agglomeration of the particles of the raw material. There are two type of equipment complying with this technology.

This dosage form is easier to administer, particularly helpful to patients, like children, who are not able to swallow capsules or tablets. However, the manufaturing of them is more complex than conventional forms, especially in selecting technology and processing equipment

Inspecting tooling and press components for wear or defects could be the most important step in improving tablet quality. There are certain inspection points that are easy to overlook yet can cause significant tablet quality issues and limit tool life. Spend a little time checking the following items for wear or defects to quickly increase tablet quality and reduce tooling cost

The pharmaceutical industry follows the most stringent requirements for manufacturing processes and used equipment also must comply with good manufacturing practices (GMP). As drug development trends change, so do manufacturing processes, much of which can now be automated...